Tennessee · Clinical guide

Ketamine Therapy for depression

Depression is a debilitating disorder marked by low energy and loss of interest. Ketamine for depression has been shown to provide rapid relief, often when other treatments have failed.

What a course of treatment looks like

  1. 1

    Free consultation

    A clinician reviews your history, current medications and goals, then confirms whether ketamine is a safe fit for you.

  2. 2

    Medical screening

    Blood pressure, heart health and any medication interactions are checked before your first session.

  3. 3

    First infusion

    A low dose is given by IV over about 40 minutes in a calm, monitored room. Someone else drives you home.

  4. 4

    Initial series

    Most people complete about six infusions over two to three weeks while the team tracks how you feel.

  5. 5

    Boosters as needed

    Occasional maintenance infusions help sustain your results, scheduled around how you respond.

Tennessee clinics treating depression

12 of 32 verified clinics list this condition.

Athena Care Nashville

220 Athens Way, Nashville

4.6(1022 Google reviews)

Athena Care Nashville is an outpatient mental health facility located in Nashville, Tennessee, serving the community for over two decades. The practice offers comprehensive behavioral health services, including diagnostic evaluations, medication management, and therapy for individuals, couples, and families. Care is delivered by a multidisciplinary clinical team that includes psychiatrists, psychiatric mental health nurse practitioners, licensed psychologists, and licensed therapists.

IM ketamine
Telehealth
Psychotherapy
+4 more
(615) 320-1155View profile →

Synaptic Psych

5300 Maryland Way #103, Brentwood

4.8(209 Google reviews)

Synaptic Psych is a medical practice located at 5300 Maryland Way in Brentwood, Tennessee. The clinic provides psychiatric and mental health services to individuals in the surrounding community.

Ketamine therapy
Telehealth
Medication management
+3 more
(615) 224-9800View profile →

Synaptic Psych - Nashville Psychiatrist

2125 Belcourt Ave, Nashville

4.8(171 Google reviews)

Synaptic Psych - Nashville Psychiatrist is a mental health practice based in Nashville, Tennessee, located at 2125 Belcourt Avenue. The clinic serves individuals seeking psychiatric care within the Nashville area.

Ketamine therapy
Medication management
Psychotherapy
+2 more
(615) 224-9800View profile →

Tennessee Ketamine & Wellness Center

1909 Mallory Ln Ste 300, Franklin

5.0(128 Google reviews)

Tennessee Ketamine & Wellness Center is a specialized medical practice located in Franklin, Tennessee. Led by a board-certified anesthesiologist with expertise in pain management, the clinic provides physician-supervised ketamine therapy, maintaining a physician on-site for treatments.

Spravato
IV ketamine infusion
(615) 813-5006View profile →

Serotonin Centers Greenhills

3900 Hillsboro Pike #20, Nashville

4.8(125 Google reviews)

Serotonin Centers Greenhills is a medical spa and anti-aging wellness center located in Nashville, Tennessee. The facility offers personalized programs focused on hormone optimization, medical aesthetics, weight management, and general wellness.

Free consult
(615) 239-5327View profile →

Synaptic Psych

3800 Gallatin Pike, Nashville

4.7(93 Google reviews)

Synaptic Psych is a clinical practice located at 3800 Gallatin Pike in Nashville, Tennessee. The clinic operates within the greater Nashville metropolitan area, serving local individuals seeking specialized psychiatric and mental health services.

Ketamine therapy
Medication management
Psychotherapy
+2 more
(615) 224-9800View profile →

Lotus Wellness

1003 Gallatin Ave Ste 100, Nashville

4.7(73 Google reviews)

Lotus Wellness is a mental health care facility located in Nashville, Tennessee. The center offers several levels of care, including a residential treatment program, partial hospitalization programs (PHP), intensive outpatient programs (IOP), and traditional outpatient services designed to accommodate various client needs and treatment intensities.

Spravato
(615) 564-6008View profile →

Nashville Ketamine

4414 Westlawn Dr, Nashville

5.0(45 Google reviews)

Nashville Ketamine Center was established in 2012 by psychiatrist Daniel Barton, M.D., and is located in Nashville, Tennessee. The clinic specializes in psychiatrist-led ketamine therapy for patients managing challenging psychiatric conditions, including depression, bipolar depression, anxiety, and trauma-related disorders.

Ketamine therapy
(615) 601-1315View profile →

Music City Ketamine

480 Duke Dr #100, Franklin

5.0(43 Google reviews)

Music City Ketamine is an outpatient clinic located in Franklin, Tennessee, serving the greater Nashville area. Founded and led by a Certified Registered Nurse Anesthetist (CRNA), the practice provides intravenous (IV) ketamine therapy administered under physician oversight with continuous, hospital-grade vital sign monitoring.

IV ketamine infusion
Free consult
(615) 988-4600View profile →

Three Rivers Wellness - Ketamine Treatment Gallatin

1531 Hunt Club Blvd Ste 106, Gallatin

5.0(27 Google reviews)

Three Rivers Wellness is a mental health clinic located in Gallatin, Tennessee, providing care for residents of Gallatin, Nashville, and surrounding areas. The center offers innovative interventions for mental health and pain conditions, including IV ketamine infusions, Spravato nasal spray, and ExoMind transcranial magnetic stimulation (TMS). The clinic also participates in the VA Community Care Network to deliver care to eligible veterans via referrals.

Ketamine therapy
Ketamine-assisted psychotherapy
Spravato
+2 more
(629) 276-9792View profile →

Waybridge Health

2000 Richard Jones Rd #260, Nashville

5.0(15 Google reviews)

Waybridge Health was a mental health clinic with locations in Omaha, Nebraska, and Nashville, Tennessee, opening its Nashville office in the Green Hills area in early 2025. The practice offered a variety of specialized interventional mental health services, including Transcranial Magnetic Stimulation (TMS), Spravato (esketamine), and IV ketamine treatments, as well as prescription support.

Medication management
Spravato
IV ketamine infusion
+1 more
(615) 732-2150View profile →

neurocare Centers of America - Nashville Neurocare Therapy

30 Burton Hills Blvd #360, Nashville

4.6(9 Google reviews)

Nashville Neurocare Therapy's Green Hills clinic in Nashville is led by Medical Director Dr. W. Scott West, a board-certified psychiatrist with more than 30 years of experience.

Medication management
Psychotherapy
Spravato
+1 more
(615) 465-4875View profile →

Other conditions we cover

This guide is general information, not medical advice. Only a prescriber who knows your history can say whether Ketamine is right for you. If you are in crisis, call or text 988.

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