Spravato® (Esketamine) Nasal Spray in Tennessee
An FDA-approved nasal spray for treatment-resistant depression and depression with suicidal thoughts. You use it yourself in a certified clinic, then rest for about two hours while staff observe you.
Request a Free ConsultationSession
~2 hours
Typical schedule
2x weekly to start
Insurance
Often covered
Overview
How Spravato ketamine works
Spravato contains esketamine, a form of the ketamine molecule. It was approved by the FDA in 2019 for treatment-resistant depression and later for depressive symptoms in adults with suicidal thoughts or actions.
Because it's FDA approved, Spravato is the ketamine-based option most often covered by insurance. It can only be given in certified treatment centers under the Spravato REMS safety program.
Often a good fit for
- Adults with treatment-resistant depression
- People wanting insurance coverage
- Use alongside an oral antidepressant
What to Expect
- 1
Prior authorization
The clinic usually works with your insurer to approve treatment first.
- 2
Induction phase
Two sessions per week for the first four weeks.
- 3
Observation
You self-administer the spray under supervision and are monitored for at least two hours.
- 4
Maintenance
Sessions typically move to weekly, then every one to two weeks.
Benefits
- • FDA approved
- • Frequently covered by insurance
- • No IV needed
- • Strong clinical trial data
Things to consider
- • About two hours per visit
- • Fixed doses (less adjustable than IV)
- • No driving the same day
Cost
Check prior authorization, network status, deductibles, drug charges and observation fees with your clinic and insurer. Official manufacturer assistance has eligibility rules and does not guarantee coverage or a particular out-of-pocket cost.
Costs and coverage questionsOfficial Spravato patient supportCommon questions
Is Spravato the same as ketamine?
It's esketamine, one half of the ketamine molecule, delivered as a nasal spray.
Do I need to keep taking an antidepressant?
Spravato has been used alongside an oral antidepressant, and it is now also approved for use on its own. Your provider decides what fits you.
Can I use it at home?
No. Every dose must be taken in a certified clinic with monitoring.
Educational information only, not medical advice. Session times and schedules vary; your licensed clinician sets your plan. No statewide price or insurance coverage is guaranteed.
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