IV Ketamine Infusions
Most studied

IV Ketamine Infusions in Tennessee

A low, carefully measured dose flows through a small IV while you relax in a reclining chair. Your provider can adjust the dose minute by minute, and your vital signs are monitored the whole time.

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Session

40–60 min

Typical series

6 in 2–3 weeks

Setting

In clinic

Overview

How IV ketamine works

IV (intravenous) infusion is the most widely researched way to receive ketamine for depression. Most of the landmark studies — including the 2023 ELEKT-D trial comparing ketamine with ECT — used IV dosing.

Because the medicine goes directly into the bloodstream, the provider controls exactly how much you receive and can slow or stop the infusion at any moment. This precision is a big reason many clinicians consider IV the gold standard.

Often a good fit for

  • Treatment-resistant depression
  • Suicidal thoughts (with medical care)
  • Chronic pain conditions

What to Expect

  1. 1

    Screening

    A medical and mental-health evaluation, review of medications and blood pressure check.

  2. 2

    Initial series

    Usually six infusions over two to three weeks, each lasting about 40–60 minutes.

  3. 3

    Recovery

    You rest 20–30 minutes afterward and need a ride home. Most people return to normal activities the next day.

  4. 4

    Maintenance

    If you respond, occasional booster infusions may help keep results going.

Benefits

  • • Most research support
  • • Precise, adjustable dosing
  • • Continuous vital-sign monitoring
  • • Fast onset — often within days

Things to consider

  • • Usually not covered by insurance
  • • Requires a small IV line
  • • Several clinic visits in the first weeks

Cost

There is no verified statewide price. Ask your clinic for a written estimate separating assessment, medication, infusion, monitoring and follow-up fees. Confirm the cost of both the initial series and any maintenance care; coverage is not guaranteed.

Costs and coverage questionsOfficial Spravato patient support

Common questions

Does an IV ketamine infusion hurt?

Only the brief pinch of placing the IV. Most people describe the infusion itself as relaxing or dreamlike.

How soon will I feel better?

Some people notice changes after the first one or two infusions; others respond later in the series.

Can I drive after an infusion?

No. Plan for a ride home and avoid driving until the next day.

Educational information only, not medical advice. Session times and schedules vary; your licensed clinician sets your plan. No statewide price or insurance coverage is guaranteed.

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